UNC5293, a potent, orally available and highly MERTK-selective inhibitor
Hongchao Zheng, Jichen Zhao, Bing Li, Weihe Zhang, Michael A. Stashko, Katherine A. Minson, Madeline G. Huey, Yubai Zhou, H. Shelton Earp, Dmitri Kireev, Douglas K. Graham, Deborah DeRyckere, Stephen V. Frye, Xiaodong Wang
Topics & Concepts
MERTKChemistryPharmacologyTyrosine-kinase inhibitorTyrosine kinaseCancer researchReceptor tyrosine kinaseReceptorBiochemistryMedicineCancerInternal medicinePhagocytosis and Immune RegulationErythrocyte Function and PathophysiologyCell death mechanisms and regulation