Characterization of a novel Pde6b-deficient rat model of retinal degeneration and treatment with adeno-associated virus (AAV) gene therapy
Ian C. Han, Luke A. Wiley, Dalyz Ochoa, Mallory J. Lang, Brynnon E. Harman, Katie M. Sheehan, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker
Topics & Concepts
Retinitis pigmentosaRetinal degenerationGenetic enhancementBiologyAdeno-associated virusPhotoreceptor cellRetinaNeuroscienceGeneGeneticsVector (molecular biology)Recombinant DNARetinal Development and DisordersCRISPR and Genetic EngineeringRetinal Diseases and Treatments