Delivery of miR-320a-3p by gold nanoparticles combined with photothermal therapy for directly targeting Sp1 in lung cancer
Jiefei Peng, Ranran Wang, Wanru Sun, Minhua Huang, Rong Wang, Youjie Li, Pingyu Wang, Guang‐Bin Sun, Shuyang Xie
Abstract
A new and promising anticancer strategy via the use of Au-RGD-miR-320a nanoparticles, and identify miR-320a/Sp1 as a potential target for future systemic therapy against lung cancer.
Topics & Concepts
Photothermal therapyColloidal goldLung cancerCancer researchCancer therapyChemistryCancerNanoparticleNanotechnologyMedicineOncologyMaterials scienceInternal medicineRNA Interference and Gene DeliveryMicroRNA in disease regulationNanoplatforms for cancer theranostics