Coligand role in the NHC nickel catalyzed C–F bond activation: investigations on the insertion of bis(NHC) nickel into the C–F bond of hexafluorobenzene
Maximilian W. Kuntze‐Fechner, Hendrik Verplancke, Lukas Tendera, Martin Diefenbach, Ivo Krummenacher, Holger Braunschweig, Todd B. Marder, Max C. Holthausen, Udo Radius
Abstract
, a radical mechanism with fluoride abstraction and an NHC-assisted pathway are both associated with almost the same kinetic barrier.
Topics & Concepts
HexafluorobenzeneNickelCatalysisChemistryBondStereochemistryPhotochemistryMedicinal chemistryOrganic chemistryMoleculeBusinessFinanceFluorine in Organic ChemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling Reactions