3,3′-Diselenodipropionic acid (DSePA) induces reductive stress in A549 cells triggering p53-independent apoptosis: A novel mechanism for diselenides
Vishwa V. Gandhi, Khushboo Gandhi, Liladhar B. Kumbhare, Jayant Sastri Goda, Vikram Gota, K. Indira Priyadarsini, Amit Kunwar
Topics & Concepts
ApoptosisA549 cellReactive oxygen speciesChemistryCytochrome cGlutathioneEndoplasmic reticulumCytotoxicityUnfolded protein responseCell biologyOxidative stressMitochondrionCancer cellCell cultureIn vitroBiochemistryCancer researchBiologyCancerGeneticsEnzymeSelenium in Biological SystemsMetal complexes synthesis and propertiesOrganoselenium and organotellurium chemistry