Dual protease type XIII/pepsin digestion offers superior resolution and overlap for the analysis of histone tails by HX-MS
James Mullahoo, Terry Zhang, Karl R. Clauser, Steven A. Carr, Jacob D. Jaffe, Malvina Papanastasiou
Topics & Concepts
NucleosomeHistoneElectron-transfer dissociationChemistryHydrogen–deuterium exchangeChromatinBiochemistryEpigeneticsHistone codeMonomerBiophysicsComputational biologyMass spectrometryChromatographyTandem mass spectrometryBiologyDNAPolymerOrganic chemistryGeneGenomics and Chromatin DynamicsRNA and protein synthesis mechanismsAdvanced Proteomics Techniques and Applications