Genomic Features Associated with the Degree of Phenotypic Resistance to Carbapenems in Carbapenem-Resistant Klebsiella pneumoniae
Zackery P. Bulman, Fiorella Krapp, Nathan B. Pincus, Eric Wenzler, Katherine R. Murphy, Chao Qi, Egon A. Ozer, Alan R. Hauser
Abstract
, were associated with lower carbapenem MICs. Machine learning did not result in a substantial improvement in the prediction of carbapenem resistance nor did it identify novel genes associated with carbapenem resistance. These findings enhance our understanding of the many contributors to carbapenem resistance in K. pneumoniae.
Topics & Concepts
ErtapenemKlebsiella pneumoniaeCarbapenemImipenemMeropenemMicrobiologyBiologyAntibiotic resistanceGeneAntibioticsGeneticsEscherichia coliAntibiotic Resistance in BacteriaBacterial Identification and Susceptibility TestingGenomics and Phylogenetic Studies