Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson’s disease models
Wenli Dong, Jiahong Zhong, Yunqing Chen, Jinfeng Xie, Yunyun Qin, Jiangping Xu, Ningbo Cai, Mengfan Li, Lu Liu, Haitao Wang
Topics & Concepts
NeuroprotectionRotenoneSubstantia nigraLAMP1Cathepsin DIn vivoChemistryCathepsinPharmacologyCell biologyApoptosisParkinson's diseaseBiologyMedicineBiochemistryInternal medicineMitochondrionAutophagyEnzymeDiseaseBiotechnologyParkinson's Disease Mechanisms and TreatmentsSirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolism