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A sequence-activated near-infrared fluorescence probe for precisely tracking <i>in vivo</i> senescence

Jiahuan Nong, Pengcheng Li, Mingming Zhu, Yifeng Li, Changsheng Wang, Yutao Zhang, Chenxu Yan, Zhiqian Guo

2025Chemical Science6 citationsDOIOpen Access PDF

Abstract

visualization of β-gal activity in a mouse model, providing a new strategy for the accurate detection of cellular senescence.

Topics & Concepts

FluorescenceIn vivoInfraredTracking (education)Sequence (biology)ChemistrySenescenceComputational biologyBiologyBiophysicsCell biologyBiochemistryGeneticsOpticsPhysicsPedagogyPsychologyAdvanced biosensing and bioanalysis techniquesTelomeres, Telomerase, and SenescenceAdvanced Nanomaterials in Catalysis
A sequence-activated near-infrared fluorescence probe for precisely tracking <i>in vivo</i> senescence | Litcius