Blockade of CXCR4 promotes macrophage autophagy through the PI3K/AKT/mTOR pathway to alleviate coronary heart disease
Fangqin Li, Jin Peng, Yanlin Lu, Ming Zhou, Jingwei Liang, Cuiyun Le, Jiuyang Ding, Jiawen Wang, Jialin Dai, Changwu Wan, Jie Wang, Peng Luo, Bing Xia
Topics & Concepts
MedicinePI3K/AKT/mTOR pathwayAutophagyCXCR4BlockadeProtein kinase BMacrophageSirolimusDiseaseCoronary heart diseaseCancer researchCell biologyInternal medicineSignal transductionInflammationChemokineApoptosisReceptorBiochemistryIn vitroBiologyChemistryAutophagy in Disease and TherapyImmune cells in cancerAtherosclerosis and Cardiovascular Diseases