Rapid and specific duplex detection of methicillin-resistant <i>Staphylococcus aureus</i> genes by surface-enhanced Raman spectroscopy
Phani R. Potluri, Vinoth Kumar Rajendran, Anwar Sunna, Yuling Wang
Abstract
input copies within 80 min. This demonstrated the potential of the SERS-PCR based approach for the accurate identification of MRSA at an early-diagnosis stage. This study also provides an alternative approach to the existing methods for detecting clinical targets without compromising sensitivity and selectivity, and with minimal handling steps. We thus believe that this approach will find a broad application in clinical applications.
Topics & Concepts
Raman spectroscopyStaphylococcus aureusSpectroscopySurface-enhanced Raman spectroscopyMethicillin-resistant Staphylococcus aureusGeneMaterials scienceMicrobiologyChemistryBiologyRaman scatteringBacteriaOpticsGeneticsBiochemistryPhysicsQuantum mechanicsSpectroscopy Techniques in Biomedical and Chemical ResearchBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniques