Synthesis and evaluation of antibacterial activity of new thieno[2,3-d]pyrimidine hybrid compounds targeting dihydropteroate synthase to combat antibiotic resistance
Rasha A. Hassan, Mohammed I.A. Hamed, Amr M. Abdou, Riham H. Hedia, Eman S. Ibrahim, Ehab A. Fouad, Sally S. Alam, Yara El‐Dash
Topics & Concepts
Dihydropteroate synthaseChemistryPyrimidineAntibacterial activityAntibioticsAntibiotic resistanceCombinatorial chemistryStereochemistryBiochemistryBacteriaPyrimethamineBiologyGeneticsImmunologyMalariaPlasmodium falciparumBiochemical and Molecular ResearchSynthesis and biological activityHIV/AIDS drug development and treatment