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Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma

Alexander Schäfer, Bénédicte Haenig, Julie Erupathil, Panja Strickner, Daniela Sabato, Richard W.D. Welford, Lhéanna Klaeylé, Simon Élise, Clemens Krepler, Patricia Brafford, Min Xiao, Meenhard Herlyn, Matthias Gstaiger, François Lehembre, Imke Renz

2021Oncogene12 citationsDOI

Topics & Concepts

MAPK/ERK pathwayMelanomaBiologyCancer researchSignal transductionMEK inhibitorEndothelin 3Endothelin receptorPharmacologyReceptorCell biologyEndothelinsGeneticsMelanoma and MAPK Pathwaysmelanin and skin pigmentationCutaneous Melanoma Detection and Management
Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma | Litcius