A selective purine-based fluorescent chemosensor for the “naked-eye” detection of zinc ions (Zn<sup>2+</sup>): applications in live cell imaging and test strips
Haiyan Xu, Wei Chen, Weixia Zhang, Lixin Ju, Hongfei Lu
Abstract
In this work, a novel purine based probe <bold>PTAHN</bold> was successfully designed and synthesized. <bold>PTAHN</bold> displayed high selectivity towards Zn<sup>2+</sup><italic>via</italic> turn-on fluorescence. What's more, <bold>PTAHN</bold> can be proficiently employed for imaging Zn<sup>2+</sup> in living cells.
Topics & Concepts
ChemistryFluorescenceNaked eyeLive cell imagingZincSelectivityIonDetection limitCellOpticsChromatographyBiochemistryOrganic chemistryPhysicsCatalysisMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniquesLuminescence and Fluorescent Materials