Genetic networks in Parkinson’s and Alzheimer’s disease
Jack Kelly, Rana Moyeed, Camille Carroll, Shouqing Luo, Xinzhong Li
Abstract
identified as potential targets for therapeutic treatments of AD. Our study demonstrated that PD and AD share common disrupted genetics and identified novel pathways, hub genes and TFs that may be new areas for mechanistic study and important targets in both diseases.
Topics & Concepts
DiseaseParkinson's diseaseBiologyNeuroscienceGeneInsulin receptorInsulin resistanceMedicineBioinformaticsGeneticsDiabetes mellitusInternal medicineEndocrinologyParkinson's Disease Mechanisms and TreatmentsNuclear Receptors and SignalingAlzheimer's disease research and treatments