Homeostasis and transitional activation of regulatory T cells require c-Myc
Jordy Saravia, Hu Zeng, Yogesh Dhungana, Daniel Bastardo Blanco, Thanh-Long M. Nguyen, Nicole M. Chapman, Yanyan Wang, Apurva Kanneganti, Shaofeng Liu, Jana Raynor, Peter Vogel, Geoffrey Neale, Peter Carmeliet, Hongbo Chi
Abstract
c-Myc coordinates context-dependent homeostasis and transitional activation with metabolic programming of regulatory T cells.
Topics & Concepts
HomeostasisCell biologyBiologyChemistryT-cell and B-cell ImmunologyImmune Cell Function and InteractionCAR-T cell therapy research