The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma
Jianbo Wu, F. Meng, Danyang Ran, Yalong Song, Yalong Song, Yunkun Dang, Fan Lai, Longyan Yang, Mi Deng, Yuqin Song, Yuqin Song, Jun Zhu
Abstract
Cells utilize different metabolic processes to maintain their growth and differentiation. Tumor cells have made some metabolic changes to protect themselves from malnutrition. These metabolic alterations affect the tumor microenvironment and macroenvironment. Developing drugs targeting these metabolic alterations could be a good direction. In this review, we briefly introduce metabolic changes/regulations of the tumor macroenvironment and microenvironment and summarize potential drugs targeting the metabolism in diffuse large B-cell lymphoma.
Topics & Concepts
LymphomaImmune systemTumor microenvironmentMetabolismCancer researchCell metabolismBiologyMetabolic activityMetabolic pathwayMetabolic regulationTumor cellsCell biologyImmunologyBiochemistryPhysiologyCancer, Hypoxia, and MetabolismAcute Myeloid Leukemia ResearchBiochemical and Molecular Research