Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the <i>Drosophila</i> Larval Model
Elodie Ramond, Anne Jamet, Xiongqi Ding, Daniel Euphrasie, Clémence Bouvier, Louison Lallemant, Xiangyan He, Laurence Arbibe, Mathieu Coureuil, Alain Charbit
Abstract
The pathogenicity of methicillin-resistant S. aureus (MRSA) strains relies on their ability to produce a wide variety of tightly regulated virulence factors. Current in vivo models to analyze host-pathogen interactions are limited and difficult to manipulate.
Topics & Concepts
MicrobiologyStaphylococcus aureusBiologyVirulenceInnate immune systemImmune systemPathogenSalmonella entericaStaphylococcal infectionsAntimicrobial peptidesAntimicrobialBacteriaImmunologyGeneSalmonellaGeneticsInvertebrate Immune Response MechanismsInsect symbiosis and bacterial influencesInsect Utilization and Effects