Detection of chemotherapy-resistant patient-derived acute lymphoblastic leukemia clones in murine xenografts using cellular barcodes
Sabrina Jacobs, Albertina Ausema, Erik Zwart, Ellen Weersing, Gerald de Haan, Leonid Bystrykh, Mirjam E. Belderbos
Topics & Concepts
Somatic evolution in cancerLeukemiaBiologyVincristineChemotherapyCancer researchclone (Java method)Acute lymphocytic leukemiaMethotrexateImmunologyDexamethasoneOncologyCyclophosphamideMedicineCancerLymphoblastic LeukemiaGeneGeneticsEndocrinologySingle-cell and spatial transcriptomicsHematopoietic Stem Cell TransplantationCancer Genomics and Diagnostics