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Mosaic loss of chromosome Y characterises late-onset rheumatoid arthritis and contrasting associations of polygenic risk score based on age at onset

Shunsuke Uchiyama, Yuki Ishikawa, Katsunori Ikari, Suguru Honda, Keiko Hikino, Eiichi Tanaka, Yoichiro Kamatani, Takahisa Gono, Giulio Genovese, Masataka Kuwana, Chikashi Terao

2025Annals of the Rheumatic Diseases9 citationsDOI

Topics & Concepts

MedicineRheumatoid arthritisPolygenic risk scoreMosaicAge of onsetInternal medicineGeneticsDiseaseGeneGenotypeSingle-nucleotide polymorphismBiologyArchaeologyHistoryRheumatoid Arthritis Research and TherapiesGenetic Associations and EpidemiologyGenomic variations and chromosomal abnormalities
Mosaic loss of chromosome Y characterises late-onset rheumatoid arthritis and contrasting associations of polygenic risk score based on age at onset | Litcius