Leveraging the predictive power of 3D organoids in dogs to develop new treatments for man and man’s best friend
Karin Allenspach, Yana Zavros, Mohamed Elbadawy, Christopher Zdyrski, Jonathan P. Mochel
Abstract
Recent progress in adult stem cell technology, along with interdisciplinary collaboration in the field of One Health, has accelerated the development of 3D organoid cultures in non-model animals, such as dogs. These advancements have the potential to significantly impact disease modeling and drug development for many diseases shared between man and man’s best friend.
Topics & Concepts
OrganoidBiologyDrug developmentComputational biologyDrug discoveryStem cellBioinformaticsPhysiologyNeuroscienceDrugCell biologyPharmacologyCancer Cells and MetastasisCancer Genomics and Diagnostics3D Printing in Biomedical Research