Acrylamide induces ferroptosis in HSC-T6 cells by causing antioxidant imbalance of the XCT-GSH-GPX4 signaling and mitochondrial dysfunction
Yuan Yuan, Yucai Li, Li Lü, Hui Liu, Yong Pang, Haiyang Yan
Topics & Concepts
GPX4MitochondrionOxidative stressCell biologyAntioxidantGlutathioneHepatic stellate cellChemistryReactive oxygen speciesMitochondrial ROSProgrammed cell deathBiochemistryBiologyApoptosisSuperoxide dismutaseEndocrinologyEnzymeGlutathione peroxidaseCancer, Lipids, and MetabolismFerroptosis and cancer prognosisCholesterol and Lipid Metabolism