Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
Jingjing Chen, Yalei Li, Jie Zhang, Minmin Zhang, Aihuan Wei, Hong‐Chun Liu, Zhicheng Xie, Wenming Ren, Wenwen Duan, Zhuo Zhang, Aijun Shen, Youhong Hu
Topics & Concepts
ChemistryPharmacophoreBRD4EpigeneticsBromodomainHDAC1HistoneHDAC6AcetylationHistone deacetylaseCell biologyCancer researchBiochemistryBiologyDNAGeneProtein Degradation and InhibitorsHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and Analysis