Human CXCL17 binds and activates fish GPR25 orthologs
Wenfeng Hu, Juanjuan Wang, Jie Yu, Junjie Yao, Yali Liu, Zeng‐Guang Xu, Zhan‐Yun Guo
Topics & Concepts
HEK 293 cellsZebrafishBiologyTransfectionRecombinant DNAMutantReceptorChemokine receptorG protein-coupled receptorChimera (genetics)GeneCell biologyChordateEmbryonic stem cellHuman genomeFish <Actinopterygii>GeneticsCricetulusChemotaxisPlasma protein bindingLigand (biochemistry)Binding siteChinese hamster ovary cellCellAgonistPhenotypeConserved sequenceChemokine receptors and signalinginterferon and immune responsesCytokine Signaling Pathways and Interactions