Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice
Maite Marcantoni, Andrea Fuchs, Peter Löw, Dušan Bartsch, Ole Kiehn, Carmelo Bellardita
Abstract
Prolonged treatment with nimodipine soon after spinal cord injury in mice prevents spasticity by blocking L-type calcium channels Ca V 1.3.
Topics & Concepts
NimodipineSpasticitySpinal cord injuryMedicineSpinal cordAnesthesiaCalciumInternal medicinePsychiatrySpinal Cord Injury ResearchNerve injury and regenerationTranscranial Magnetic Stimulation Studies