Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages
Xuelian Zhao, Liang Yu, Sun-Dong Zhang, Ping Kou, Haiyan Ni, Xiangyu Qin, Chun-Jian Zhao, Wei Wang, Thomas Efferth, Yujie Fu
Topics & Concepts
Downregulation and upregulationOxidative stressChemistryPhosphorylationKinaseAntioxidantChlorogenic acidNF-κBCell biologyCaffeic acidOxidative phosphorylationIκBαKEAP1MAPK/ERK pathwayTumor necrosis factor alphaSignal transductionBiochemistryBiologyImmunologyGeneTranscription factorFood scienceNatural product bioactivities and synthesisGenomics, phytochemicals, and oxidative stressBiological Activity of Diterpenoids and Biflavonoids