Inhibition of autophagy aggravates DNA damage response and gastric tumorigenesis via Rad51 ubiquitination in response to <i>H. pylori</i> infection
Chuan Xie, Nianshuang Li, Huan Wang, Cong He, Yi Hu, Chao Peng, Yaobin Ouyang, Dejie Wang, Yong Xie, Chen Jiang, Xu Shu, Yin Zhu, Nonghua Lü
Abstract
infection, autophagy, DNA damage and gastric tumorigenesis.
Topics & Concepts
AutophagyBiologyCarcinogenesisDNA damageCancer researchHelicobacter pyloriRAD51Downregulation and upregulationCagACancerDNA repairGene knockdownApoptosisDNAGeneticsVirulenceGeneHelicobacter pylori-related gastroenterology studiesRNA modifications and cancerAutophagy in Disease and Therapy