Electrochemical Scalable Sulfoxidation of Sulfides with Molecular Oxygen and Water
Zhen Cheng, Xing‐Lian Gao, Lingling Yao, Zhaoxin Wei, Guohui Qin, Yonghong Zhang, Bin Wang, Yu Xia, Ablimit Abdukader, Fei Xue, Weiwei Jin, Chenjiang Liu
Abstract
Abstract An efficient and chemoselective synthesis of sulfoxides through the electrooxidation of sulfides has been well developed. This protocol takes advantage of electricity as the terminal oxidant and of molecular oxygen and water as the oxygen atom sources. A variety of structurally diverse sulfoxide compounds are assembled in moderate to excellent yields. The scaled‐up reactions at 6–20 mmol show the good practicability and application potential of this methodology. A possible free radical mechanism has been proposed to rationalize the reaction procedure.
Topics & Concepts
ChemistryElectrochemistrySulfoxideMolecular oxygenCombinatorial chemistryOxygenOxygen atomDimethyl sulfoxideOrganic chemistryMoleculeElectrodePhysical chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsChemical Synthesis and Reactions