Female adipose tissue has improved adaptability and metabolic health compared to males in aged obesity
Mita Varghese, Cameron Griffin, Kaitlin McKernan, Leila Eter, Simin Abrishami, Kanakadurga Singer
Abstract
in both sexes. Our studies suggest that even with aging, female GWAT shows an attenuated inflammatory response compared to males due to an efficient oxidative metabolism combined with an active tissue remodeling state.
Topics & Concepts
Adipose tissueInternal medicineEndocrinologyObesityInflammationWhite adipose tissueProinflammatory cytokineFibrosisLipolysisMedicineAdipokineBiologyInsulin resistanceAdipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismCardiovascular Disease and Adiposity