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Computational investigation to identify potent inhibitors of the GTPase-Kirsten RAt sarcoma virus (K-Ras) mutants G12C and G12D

S. Udhaya Kumar, C. George Priya Doss

2021Computers in Biology and Medicine26 citationsDOI

Topics & Concepts

MutantDocking (animal)Cancer researchChemistryIn vitroIn vivoPharmacologyBiologyBiochemistryMedicineGeneticsGeneNursingProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerCell death mechanisms and regulation
Computational investigation to identify potent inhibitors of the GTPase-Kirsten RAt sarcoma virus (K-Ras) mutants G12C and G12D | Litcius