Irradiated chimeric antigen receptor engineered NK-92MI cells show effective cytotoxicity against CD19+ malignancy in a mouse model
Qian Liu, Yingxi Xu, Junli Mou, Kejing Tang, Xuehang Fu, Yihui Li, Yanyan Xing, Qing Rao, Haiyan Xing, Zheng Tian, Min Wang, Jianxiang Wang
Topics & Concepts
Chimeric antigen receptorCytotoxicityInterleukin 21Cancer researchCD19ImmunotherapyNK-92Interleukin 12ImmunologyLymphomaAntigenBiologyIn vitroCytotoxic T cellImmune systemCD8BiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses