Litcius/Paper detail

Apps and the Woman With Gestational Diabetes Mellitus

Jincy Immanuel, David Simmons

2021Diabetes Care17 citationsDOI

Abstract

Gestational diabetes mellitus (GDM) affects 1–45% of pregnancies depending on the population and diagnostic criteria selected (1). A meta-analysis with 12 randomized controlled trials (RCTs) showed that GDM management improves pregnancy outcomes (2). GDM management involves counseling, dietary modification, physical activity, glucose monitoring, and, where glycemic thresholds are exceeded, supplemental pharmacological therapies. Implementation varies, with possible consequences for the pregnancy outcomes. For example, the Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) and Maternal–Fetal Medicine Units Network (MFMUN) RCTs, the two largest GDM treatment trials, differed in their insulin use (20% vs. 8%, respectively) and outcomes (3,4). Within the MFNUM RCT, the median glucose achieved was 10–12 mg/dL (0.6 mmol/L) higher in the insulin-treated than the non–insulin-treated group, particularly after dinner, when 50% of the self–blood glucose monitoring results were over the target glucose (median glucose was 120 mg/dL [6.7 mmol/L]). The more self–blood glucose monitoring results occur above target, the greater the chance of an adverse pregnancy outcome. In one study, adverse outcomes occurred in 25% vs. 60% of births among those with none vs. >30% above-target results, respectively (5). There are multiple barriers to GDM management for women with GDM (6). Besides a range of socioeconomic, service, and access barriers, women may experience misunderstanding or confusion over the advice provided, as well as a range of emotional and psychological challenges. Meanwhile, the increasing number of women with GDM (7) has created greater pressure on health care providers to streamline their services with different models of care, often sharing management with non–diabetes service staff (8). New technologies …

Topics & Concepts

MedicineGestational diabetesPregnancyGlycemicRandomized controlled trialDiabetes mellitusInsulinPopulationObstetricsBlood Glucose Self-MonitoringAdverse effectInternal medicineGestationEndocrinologyEnvironmental healthBiologyGeneticsContinuous glucose monitoringGestational Diabetes Research and ManagementMaternal and fetal healthcarePregnancy and preeclampsia studies