Microbiota-induced inflammatory responses in bladder tumors promote epithelial-mesenchymal transition and enhanced immune infiltration
Qiang Li, Yichao Sun, Kun Zhai, Bingzhi Geng, Zhenkun Dong, Lei Ji, Hui Chen, Yan Cui
Abstract
The intratumoral microbiota may mediate the bladder tumor inflammatory response, thereby promoting the epithelial-mesenchymal transition program and influencing tumor immune infiltration.
Topics & Concepts
Infiltration (HVAC)Immune systemEpithelial–mesenchymal transitionInflammationTransition (genetics)Cancer researchMesenchymal stem cellPathologyMedicineChemistryImmunologyMaterials scienceGeneBiochemistryComposite materialBladder and Urothelial Cancer TreatmentsGut microbiota and healthTryptophan and brain disorders