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N-acetylcysteine as an adjunctive treatment for bipolar depression and major depressive disorder: a systematic review and meta-analysis of double-blind, randomized placebo-controlled trials

Taro Kishi, Nobumi Miyake, Makoto Okuya, Kenji Sakuma, Nakao Iwata

2020Psychopharmacology37 citationsDOI

Topics & Concepts

PlaceboStrictly standardized mean differenceInternal medicineDiscontinuationRandomized controlled trialManiaMedicineAdjunctive treatmentYoung Mania Rating ScaleMeta-analysisClinical Global ImpressionDepression (economics)Confidence intervalAdverse effectBipolar disorderPhysical therapyAlternative medicineLithium (medication)MacroeconomicsEconomicsPathologyBipolar Disorder and TreatmentTryptophan and brain disordersFolate and B Vitamins Research
N-acetylcysteine as an adjunctive treatment for bipolar depression and major depressive disorder: a systematic review and meta-analysis of double-blind, randomized placebo-controlled trials | Litcius