A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology
Jinhong Wie, Zhenjiang Liu, Haikun Song, Thomas F. Tropea, Lu Yang, Huanhuan Wang, Yuling Liang, Chunlei Cang, Kimberly Aranda, Joey Lohmann, Jing Yang, Boxun Lu, Alice Chen‐Plotkin, Kelvin C. Luk, Dejian Ren
Topics & Concepts
IntracellularProtein kinase BExtracellularParkinson's diseaseLoss functionCell biologyBiologyAutophagyLRRK2NeuroscienceGrowth factorPhosphorylationOrganelleDiseaseInternal medicineMedicineGeneticsGenePhenotypeReceptorApoptosisCalcium signaling and nucleotide metabolismCellular transport and secretionSignaling Pathways in Disease