Thieno[3,4- <i>d</i> ]pyrimidin-4(3 <i>H</i> )-thione: an effective, oxygenation independent, heavy-atom-free photosensitizer for cancer cells
Luis A. Ortiz‐Rodríguez, Ye‐Guang Fang, Germain Niogret, Kaivin Hadidi, Sean J. Hoehn, Heather J. Folkwein, Steffen Jockusch, Yitzhak Tor, Ganglong Cui, Liraz Levi, Carlos E. Crespo‐Hernández
Abstract
It is demonstrated that thieno[3,4- d ]pyrimidin-4(3 H )-thione is an effective, oxygenation independent, heavy-atom-free photosensitizer against mono-layer of melanoma and cervical cancer cells.
Topics & Concepts
PhotosensitizerChemistrySinglet oxygenQuantum yieldPyrimidinePhotochemistryNucleobaseFluorescenceDNAStereochemistryOxygenOrganic chemistryPhysicsQuantum mechanicsBiochemistryPhotodynamic Therapy Research StudiesNanoplatforms for cancer theranosticsPorphyrin and Phthalocyanine Chemistry