Synthesis, biological evaluation and structure-activity relationship of 2-(2-hydroxyaryl)alkenylphosphonium salts with potency as anti-MRSA agents
Natalia V. Terekhova, Anna P. Lyubina, Alexandra D. Voloshina, Anastasiya S. Sapunova, Khasan R. Khayarov, Daut R. Islamov, Konstantin S. Usachev, Vladimir G. Evtugyn, D. A. Tatarinov, В. Ф. Миронов
Topics & Concepts
ChemistryAntimicrobialPhosphoniumBacteriaStaphylococcus aureusLipophilicityPotencyMoietyBiological activityBioassayMechanism of actionIn vitroMode of actionGram-positive bacteriaGram-negative bacteriaStereochemistryBiochemistryMicrobiologyOrganic chemistryEscherichia coliBiologyGeneGeneticsOrganophosphorus compounds synthesisSynthesis and biological activityPhosphorus compounds and reactions