Understanding how health interventions or exposures produce their effects using mediation analysis
Aidan G Cashin, James H. McAuley, Tyler J. VanderWeele, Hopin Lee
Abstract
Mediation analysis is a method that quantifies how health exposures, such as medical interventions, change patient outcomes. Evidence that is generated from mediation analyses is important for intervention development and clinical and policy decision making. Mediation analysis has many applications that require specific and careful consideration for design, conduct, analysis, and interpretation. This article outlines motivations, effect types, causal assumptions, estimation, and reporting guidance for mediation analysis studies that aim to improve their conduct, interpretation, and implementation.
Topics & Concepts
MediationPsychological interventionIntervention (counseling)PsychologyInterpretation (philosophy)Applied psychologyComputer scienceSociologySocial sciencePsychiatryProgramming languageHealth Policy Implementation ScienceHealth Systems, Economic Evaluations, Quality of LifeAdvanced Causal Inference Techniques