Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors
Oliver Pilgram, Aline Keils, Gerrit E. Benary, Janis A. Müller, Stefan Merkl, Sandrine Ngaha, Simon Huber, Florent Chevillard, Anne Harbig, Viktor Magdolen, A. Heine, Eva Böttcher‐Friebertshäuser, Torsten Steinmetzer
Topics & Concepts
ChemistrySelectivityThrombinMonobasic acidRational designStructure–activity relationshipStereochemistryBiochemistryIn vitroCombinatorial chemistryNanotechnologyOrganic chemistryImmunologyMaterials scienceCatalysisPlateletBiologyInfluenza Virus Research StudiesProtein Structure and DynamicsNeonatal Health and Biochemistry