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Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites

Silvia Giatti, Silvia Diviccaro, Eva Falvo, Luis Miguel García‐Segura, Roberto Cosimo Melcangi

2020Frontiers in Neuroendocrinology29 citationsDOIOpen Access PDF

Topics & Concepts

Neuroactive steroidTestosterone (patch)Central nervous systemOxidoreductaseEndocrinologyInternal medicineEnzymeBiologyPathologicalReceptorBiochemistryMedicineGABAA receptorHormonal Regulation and HypertensionHormonal and reproductive studiesEstrogen and related hormone effects
Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites | Litcius