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Accuracy of two dosimetry software programs for 177Lu radiopharmaceutical therapy using voxel-based patient-specific phantoms

Keamogetswe Ramonaheng, J.A. van Staden, Hanlie du Raan

2022Heliyon10 citationsDOIOpen Access PDF

Abstract

Purpose: Virtual dosimetry using voxel-based patient-specific phantoms and Monte Carlo (MC) simulations offer the advantage of having a gold standard against which absorbed doses may be benchmarked to establish the dosimetry accuracy. Furthermore, these reference values assist in investigating the accuracy of the absorbed dose methodologies from different software programs. Therefore, this study aimed to compare the accuracy of the absorbed doses computed using LundADose and OLINDA/EXM 1.0. Methods: . Results: reflects self-doses plus cross-doses. Conclusion: Lu dosimetry for clinical applications.

Topics & Concepts

DosimetryVoxelNuclear medicineAbsorbed doseMonte Carlo methodIterative reconstructionInternal dosimetrySpect imagingMedical physicsMedicineComputer scienceMathematicsRadiologyStatisticsRadiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and ApplicationsAdvanced Radiotherapy Techniques
Accuracy of two dosimetry software programs for 177Lu radiopharmaceutical therapy using voxel-based patient-specific phantoms | Litcius