Synthesis of di(hetero)aryl sulfides by defluorinative sulfenylation of polyfluoroalkyl ketones with sodium sulfinates or arylsulfonyl chlorides
Xue‐Qiang Chu, Ting Xie, Ya‐Wen Wang, Xiang-Rui Li, Weidong Rao, Haiyan Xu, Zhi‐Liang Shen
Abstract
Cascade reactions of α-perfluoroalkyl ketones with sodium sulfinates or arylsulfonyl chlorides that allowed the efficient synthesis of fluoroalkylated di(hetero)aryl sulfide derivatives under transition metal-free conditions were developed.
Topics & Concepts
ChemistryMoietyArylSulfideSodium sulfideSulfurTandemAnnulationMoleculeCleavage (geology)SodiumCombinatorial chemistryMedicinal chemistryOrganic chemistryCatalysisMaterials scienceGeotechnical engineeringComposite materialFracture (geology)EngineeringAlkylSulfur-Based Synthesis TechniquesFluorine in Organic ChemistryChemical Synthesis and Reactions