Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A
Bin Xiong, Junwei Huang, Yan Liu, Min Zou, Zhibo Zhao, Jianping Gong, Xiaoling Wu, Chan Qiu
Topics & Concepts
UbiquitinDeubiquitinating enzymeCancer researchGene silencingCell growthProteasomeDownregulation and upregulationCell biologyChemistryProtein degradationBiologyBiochemistryGeneUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and DiseaseMicrotubule and mitosis dynamics