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The efficacy of vancomycin powder in total knee arthroplasty

Wazzan Aljuhani, Abdullah Alanazi, Mohammad Alghafees, Sondos H. Sagor, Ali A Alhandi

2021Saudi Medical Journal19 citationsDOIOpen Access PDF

Abstract

OBJECTIVES: To assess the efficacy of vancomycin powder (VP) in total knee arthroplasty (TKA). METHODS: The study design was retrospective cohort. All patients who underwent primary TKA for osteoarthritis between January 1, 2018, and March 1, 2020, in King Abdulaziz Medical City, Riyadh, Saudi Arabia were included (n=98). Of the total participants, 48 participants in the experimental group matched with 48 participants in the control group were included in the final study sample. Numerical variables are reported as means, standard deviations, and standard errors. The hypothesis was tested using the Chi-square test and independent t-test. RESULTS: =0.31). CONCLUSION: We found no significant differences in the infection rates following primary TKA when using VP.

Topics & Concepts

MedicineTotal knee arthroplastyVancomycinRetrospective cohort studyCohortOsteoarthritisArthroplastySurgeryInternal medicineStaphylococcus aureusBiologyGeneticsAlternative medicinePathologyBacteriaOrthopedic Infections and TreatmentsAntimicrobial agents and applicationsSurgical site infection prevention
The efficacy of vancomycin powder in total knee arthroplasty | Litcius