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Palladium Catalyzed Ring Expansion Reaction of Isoxazolones with Isocyanides: Synthesis of 1,3‐Oxazin‐6‐One Derivatives

Yiming Zhu, Wan Zhang, Hongkun Li, Xiaoping Xu, Shun‐Jun Ji

2020Advanced Synthesis & Catalysis16 citationsDOI

Abstract

Abstract A palladium catalyzed ring expansion reaction of isoxazolones with isocyanides was disclosed. In the reaction, a cascade process involving ring‐opening/cyclization was suggested. The reaction features high atomic economy due to no elimination of CO 2 occurred. Moreover, products obtained demonstrate aggregation‐induced emission properties with relatively high solid‐state emission efficiencies. magnified image

Topics & Concepts

ChemistryPalladiumRing (chemistry)CatalysisCascadeCascade reactionReaction conditionsCombinatorial chemistryOrganic chemistryChromatographyFluorine in Organic ChemistryLuminescence and Fluorescent MaterialsRadical Photochemical Reactions
Palladium Catalyzed Ring Expansion Reaction of Isoxazolones with Isocyanides: Synthesis of 1,3‐Oxazin‐6‐One Derivatives | Litcius