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A heavy-metal-free desulfonylative Giese-type reaction of benzothiazole sulfones under visible-light conditions

Tetsuya Sengoku, Daichi Ogawa, Haruka Iwama, Toshiyasu Inuzuka, Hidemi Yoda

2021Chemical Communications18 citationsDOI

Abstract

A visible-light-induced desulfonylative Giese-type reaction has been developed. Essential to the success is the employment of Hantzsch ester to activate benzothiazole sulfones without any heavy-metal additives. Not only benzylic benzothiazole sulfones but also alkyl ones were viable substrates and reacted with electron-deficient alkenes and a propiol amide.

Topics & Concepts

BenzothiazoleChemistryMetalPhotochemistryVisible spectrumPolymer chemistryOrganic chemistryMaterials scienceOptoelectronicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods
A heavy-metal-free desulfonylative Giese-type reaction of benzothiazole sulfones under visible-light conditions | Litcius