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USP3 deubiquitinates and stabilizes the adapter protein ASC to regulate inflammasome activation

Wanxin Zhuang, Lei Zhang, Yi Zheng, Bingyu Liu, Chunhong Ma, Wei Zhao, Suxia Liu, Feng Liu, Chengjiang Gao

2022Cellular and Molecular Immunology27 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomeSignal transducing adaptor proteinInnate immune systemCell biologyUbiquitinDampBiologyImmune systemActivator (genetics)RegulatorSignal transductionChemistryImmunologyInflammationReceptorBiochemistryGeneMeteorologyPhysicsInflammasome and immune disordersUbiquitin and proteasome pathwaysToxoplasma gondii Research Studies
USP3 deubiquitinates and stabilizes the adapter protein ASC to regulate inflammasome activation | Litcius