Endothelium-specific deletion of Nox4 delays retinal vascular development and mitigates pathological angiogenesis
Xixiang Tang, Joshua J. Wang, Jinli Wang, Hanna E. Abboud, Yanming Chen, Sarah X. Zhang
Topics & Concepts
NOX4AngiogenesisRetinalSprouting angiogenesisNeovascularizationNADPH oxidaseBiologyEndothelial stem cellCell biologyVascular endothelial growth factor AVascular endothelial growth factorCancer researchBiochemistryReactive oxygen speciesIn vitroVEGF receptorsAngiogenesis and VEGF in CancerRetinal Diseases and TreatmentsNeutrophil, Myeloperoxidase and Oxidative Mechanisms