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Influence of comorbidity of chronic diseases on basic activities of daily living among older adults in China: a propensity score-matched study

Hongji Zeng, Miao Chen, Rui Wang, Weijia Zhao, Wenjuan Wang, Yahui Liu, Shufan Wei, Anqi Liu, Huibing Jia, Guoxin Li, Junge Zhou, Xuejiao Chen, Qingfeng Tian

2024Frontiers in Public Health16 citationsDOIOpen Access PDF

Abstract

Rationale With the accelerating process of population aging, the comorbidity of chronic disease (CCD) has become a major public health problem that threatens the health of older adults. Objective This study aimed to assess whether CCD is associated with basic activities of daily living (BADL) and explore the factors influencing BADL in older adults. Method A cross-sectional community health survey with stratified random sampling among older residents (≥60 years old) was conducted in 2022. A questionnaire was used to collect information on BADL, chronic diseases, and other relevant aspects. Propensity score matching (PSM) was used to match the older adults with and without CCD. Univariate and multivariate logistic regression analyses were used to explore the factors influencing BADL. PSM was used to match participants with single-chronic disease (SCD) and CCD. Results Among the 47,720 participants, those with CCD showed a higher prevalence of BADL disability (13.07%) than those with no CCD (6.33%) and SCD (7.39%). After adjusting for potential confounders with PSM, 6,513 pairs of cases with and without CCD were matched. The univariate analysis found that the older adults with CCD had a significantly higher prevalence of BADL disability (13.07%, 851 of 6,513) than those without CCD (9.83%, 640 of 6,513, P < 0.05). The multivariate logistic regression analysis revealed that CCD was a risk factor for BADL in older adults [OR = 1.496, 95% CI: 1.393–1.750, P < 0.001]. In addition, age, educational level, alcohol intake, social interaction, annual physical examination, retirement benefits, depression, weekly amount of exercise, and years of exercise were related to BADL disability ( P < 0.05). PSM matching was performed on participants with CCD and SCD and showed that the older adults with CCD had a significantly higher prevalence of BADL disability (13.07%, 851 of 6,513) than those with SCD (11.39%, 742 of 6,513, P < 0.05). Conclusion The older adults with CCD are at a higher risk of BADL disability than their counterparts with no CCD or SCD. Therefore, we advocate paying attention to and taking measures to improve the health and quality of life of these individuals.

Topics & Concepts

Logistic regressionMedicineConfoundingActivities of daily livingComorbidityPropensity score matchingMultivariate analysisUnivariate analysisGerontologyCross-sectional studyMultivariate statisticsPhysical therapyInternal medicinePathologyMathematicsStatisticsChronic Disease Management StrategiesHealthcare Systems and ReformsHealth disparities and outcomes
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