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A Prospective Trial of the Microneedle Fractional Radiofrequency System Application in the Treatment of Infraorbital Dark Circles

Xianglei Wu, Ying Liu, Jiafang Zhu, Wenxin Yu, Xiaoxi Lin

2022Clinical Cosmetic and Investigational Dermatology10 citationsDOIOpen Access PDF

Abstract

Background: Infraorbital dark circles (IDC) are commonly consulted in aesthetic practice. There is not yet a multifactorial approach to facilitating their treatment. Objective: To investigate the safety and efficacy of the microneedle fractional radiofrequency (MRF) system for the treatment of IDC. Methods: A prospective, split-face, evaluator-blind clinical trial was conducted to study the change in the overall appearance, color, and wrinkles in 21 female patients with mixed type IDC before and after MFR treatment. Results: Both patients and independent evaluators found significant improvement on the global aesthetic scales after the MFR treatment, especially on periorbital wrinkles (p=0.031). Trends in decreased melanin density in the IDC area were found, but no statistical differences were established. No side effects were observed. Conclusion: MFR is a safe and effective modality for improving mixed type IDC by correcting the structural factors.

Topics & Concepts

MedicineHyperpigmentationProspective cohort studyPatient satisfactionSurgeryDermatologyDermatologic Treatments and Researchmelanin and skin pigmentationAdvancements in Transdermal Drug Delivery
A Prospective Trial of the Microneedle Fractional Radiofrequency System Application in the Treatment of Infraorbital Dark Circles | Litcius